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ea0063gp155 | Cushing's | ECE2019

Endocrine immune-related adverse events following immune checkpoint inhibitors in patients with advanced melanoma: single-center retrospective analysis

Kassi Eva , Angelousi Anna , Asonitis Nikos , Petychaki Foteini , Diamantopoulos Panayiotis , Anastasopoulou Amalia , Benopoulou Olga , Gogas Helen

Introduction: Immune-check point inhibitors (ICPis) has been shown to significantly improve survival in patients with advanced melanoma. Immune-related endocrinopathies (irEs) and in particular hypophysitis and thyroid dysfunction have been well described with an incidence varying from 917% and 3.813.2% respectively.Methods: This is a retrospective analysis of irEs in 325 (190 men) patients with melanoma receiving ICPis (PD-1/PDL-1 or CTLA-4 ...

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ea0070aep104 | Adrenal and Cardiovascular Endocrinology | ECE2020

How innocent are nonfunctioning adrenal incidentalomas?

Savelli Akrivi , Athanassouli Fani , Petychaki Fotini , Asonitis Nikos , Giovanopoulos Ilias , Samarkos Michalis , Benopoulou Olga , Kourbeti Irene , Psichogiou Mina , Mantzourani Marina , Cholongitas Evangelos , Gogas Helen , Kassi Eva , Angelousi Anna

Context: Adrenal incidentalomas (AI) can be found in 3–10% of the general population. The vast majority of them (70%) represents nonfunctioning adrenal incidentalomas (NFAI). Although several comorbidities have been studied in patients with autonomous cortisol secretion (ACS) there are limited data for those with NFAI.Aim: To study metabolic disorders frequency in patients with AI and especially NFAI.Design: Retrospective stu...

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Endocrine Abstracts

Endocrine immune-related adverse events following immune checkpoint inhibitors in patients with advanced melanoma: single-center retrospective analysis

How innocent are nonfunctioning adrenal incidentalomas?

BiosciAbstracts